FIMSA International Symposium on Autoimmune Diseases: From Basic to Clinics


“FIMSA International Symposium on Autoimmune Diseases: From Basic to Clinics”was held in Beijing Conference Center, China, from October 17 to 20, 2013, which was jointly organized by the Federation of Immunological Societies of Asia-Oceania (FIMSA), Chinese Society for Immunology (CSI), Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College Hospital. Leading immunologists, in the field of autoimmunity, from all over the globe gathered for this symposium to give speeches on the frontiers of autoimmunity, to discuss the advances in the understanding of the pathogenesis of autoimmune disease and the promising therapy strategy. This international symposium was chaired by Academician Xuetao Cao (President of FIMSA and CAMS), Professor Shigeo Koyasu (RIKEN and Keio University, Japan), Professor Gregory J Tsay (Secretary-General of FIMSA) and Professor Fengchun Zhang (Peking Union Medical College Hospital). Professor Bo Huang (CAMS) was appointed as secretary general to host this meeting.

After welcome reception dinner at the evening of 17 October, this symposium formally began at the morning of 18 October with welcoming speech given by President Xuetao Cao. Firstly, he warmly welcomed all the attendees the main purpose of this symposium. Then he gave high regards to the FIMSA for the contribution to international communications and collaborations, exploring new ideas and encouraging young scholars. He also invited all the attendees to gather in Beijing in 2019 again for the 17th International Congress of Immunology (The 17th ICI). Professor Gregory J Tsay and Professor Nicholas J.C. King (Past President of FIMSA, Discipline of Pathology, Sydney Medical School) also highly praised FIMSA symposium for the positive effects on immunologists.

The academic sessions lasting two and a half days began from 8:30 am of 18 October. The sessions were divided into five parts and contained twenty-six reports given by famous immunologists. The five sessions involving classic and leading issues of autoimmunity were: 1. B cell in autoimmunity; 2. Signaling in autoimmunity; 3. T cells in autoimmunity; 4. Therapeutics of autoimmune diseases; 5. Regulation of autoimmune response.

Session One contained five reports, including: “B cells and Autoimmunity” given by Professor Peter E. Lipsky (National Institutes of Health, Bethesda U.S.A); “Epigenetic regulation of B lymphocyte self-tolerance” given by Professor Moncef Zouali (Inserm and Paris Diderot, France); “PTENtial B cells in systemic lupus erythematosus” given by Professor Xuan Zhang (Dept. of Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, China); “Roles of regulatory B cells in autoimmune arthritis” given by Professor Liwei Lu (Dept. of Pathology, The University of Hong Kong, China); “Genetic architecture of Type 1 diabetes” given by Professor Narinder Mehra (Dept. of Transplant Immunology & Immunogenetics, All India Institute of Medical Sciences, India).

Session Two contained five reports, including: “Adaptor control of T-cell inflammatory responses” given by Professor Christopher E. Rudd (Dept. of Pathology, University of Cambridge, U.K); “Cross-regulation of innate immune response and inflammation” given by Professor Xuetao Cao (Chinese Academy of Medical Sciences, Beijing, China); “The role of Calcineurin/NFAT signaling pathway in regulating innate immunity” given by Professor Paola Ricciardi-Castagnoli (SIgN/A-STAR, Singapore); “Targeting the IL-10 pathway by RNAi has beneficial effects on the development of experimental lupus” given by Professor Gregory J Tsay (Zhongshan Medical University, Taipei, China); “IL-17 signaling and autoimmune inflammation” given by Professor Youcun Qian (Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China).

Session Three contained six reports, including: “The unbearable self-why do we lose tolerance to complement?”given by Professor Seppo Meri (Haartman Institute, University of Helsinki, Finland); “T regulatory cells in immune responses and autoimmunity” given by Dr. Wanjun Chen (National Institutes of Health, Bethesda U.S.A); “Generation of regulatory T cells (Tregs) by TGF-beta and NR4a nuclear factor” given by Professor Akihiko Yoshimura (Microbiology and Immunology, Keio University School of Medicine, Japan); “Plasmacytoid dendritic cells instigate autoantibody response by type I interferon production ” given by Professor Wei Cao (Dept. of Immunology, University of Texas M.D. Anderson Cancer Center, USA); “Novel regulatory T cell subpopulations identified by CD39 and CD45RO, and their function in AS patients” given by Professor Huji Xu (Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai, China); “Pathogenesis of skin injury of systemic lupus erythematosus” given by Professor Guo-Min Deng (Dept. of Microbiology and Immunology, Nanjing Medical University, China).

Session Four contained five reports, including: “The world of investigation into the genetics of autoimmune diseases is changing” given by Professor C. G. Fathman (Stanford University School of Medicine, U.S.A); “2013 treatment strategies for management of inflammatory joint disease (IJD)” given by Professor Tore K. Kvien (Dept. of Rheumatology, Diakonhjemmet Hospital, Norway); “Novel immune-modifying microparticles for the treatment of inflammatory monocyte-mediated disease” given by Professor Nicholas J. C. King (Sydney Medical School, Australia); “Therapeutic roles of T regulatory cells and human gingival-derived mesenchymal stem cells in autoimmune diseases” given by Professor Song-Guo Zheng (Autoimmune Disease Center, Penn State University Hershey College of Medicine, U.S.A); “Molecularly altered peptide inhibited experimental arthritis—a translational study of RA” given by Professor Zhanguo Li (Dept. of Rheumatology & Immunology, People’s Hospital, China).

Session Five contained five reports, including: “Regulation of gut homeostasis by innate immunity” given by Professor Kiyoshi Takeda (WPI Immunology Frontier Research Center, Osaka University, Japan); “Natural killer cells in autoimmune diseases” given by Professor Zhigang Tian (University of Science & Technology of China, China); “Novel insights into the biology of human Toll-like receptor 7” given by Professor Vincenzo Cerundolo (Weatherall Institute of Molecular Medicine, University of Oxford, U.K); “Function of NOD2 in Crohn’s Disease” given by Professor Alison Simmons (Nuffield Department of Medicine, University of Oxford, U.K); “Dendritic cells and Type-I diabetes” given by Professor Li Wu (Tsinghua University-Peking University Joint Center for life Sciences, Tsinghua University School of Medicine, China).

The symposium came to the end at 11:30 on 20 October. In the final, Professor Bo Huang made a summary of this symposium. In addition, he thanked FIMSA and CSI for their supports and contributions to this symposium, and thanked all the invited speakers for their outstanding reports, and all the attendees for their participation and cooperation as well. Finally, he gave his best wishes to the coming 6th FIMSA Congress in Singapore. Successfully, “The FIMSA International Symposium on Autoimmune Diseases” ended with its remarkable meaning on the progression of immunology.